The long and winding road to effective immunotherapy in patients with adrenocortical carcinoma

Salvatore Grisanti; Deborah Cosentini; Marta Laganà; Alberto Dalla Volta; Carlotta Palumbo; Guido Alberto Massimo Tiberio; Sandra Sigala; Alfredo Berruti

doi:10.2217/fon-2020-0686

The long and winding road to effective immunotherapy in patients with adrenocortical carcinoma

Future Oncol. 2020 Dec;16(36):3017-3020. doi: 10.2217/fon-2020-0686. Epub 2020 Aug 28.

Authors

Salvatore Grisanti¹, Deborah Cosentini¹, Marta Laganà¹, Alberto Dalla Volta¹, Carlotta Palumbo², Guido Alberto Massimo Tiberio³, Sandra Sigala⁴, Alfredo Berruti¹

Affiliations

¹ Medical Oncology Unit, Department of Medical & Surgical Specialties, Radiological Sciences & Public Health, University of Brescia, ASST Spedali Civili of Brescia, Brescia, 25123, Italy.
² Urology Unit, Department of Medical & Surgical Specialties, Radiological Sciences & Public Health, University of Brescia, ASST Spedali Civili of Brescia, Brescia, 25123, Italy.
³ Surgical Unit, Department of Medical & Surgical Specialties, Radiological Sciences & Public Health, University of Brescia, ASST Spedali Civili of Brescia, Brescia, 25123, Italy.
⁴ Department of Molecular & Translational Medicine, Section of Pharmacology, University of Brescia, Brescia, 25123, Italy.

PMID: 32857613
DOI: 10.2217/fon-2020-0686

No abstract available

Keywords: Adrenocortical carcinoma; PD-L1; hypercortisolism; immune checkpoints inhibitors; immunogenicity; immunotherapy; progression-free survival; tumor infiltrating lymphocytes.

Publication types

Editorial
Historical Article

MeSH terms

Adrenal Cortex Neoplasms / drug therapy*
Adrenal Cortex Neoplasms / genetics
Adrenal Cortex Neoplasms / immunology
Adrenal Cortex Neoplasms / mortality
Adrenocortical Carcinoma / drug therapy*
Adrenocortical Carcinoma / genetics
Adrenocortical Carcinoma / immunology
Adrenocortical Carcinoma / mortality
Clinical Trials as Topic
Disease Progression
Drug Resistance, Neoplasm / genetics
Drug Resistance, Neoplasm / immunology
History, 21st Century
Humans
Immune Checkpoint Inhibitors / pharmacology
Immune Checkpoint Inhibitors / therapeutic use*
Immunotherapy / history
Immunotherapy / methods*
Immunotherapy / trends
Progression-Free Survival

Substances

Immune Checkpoint Inhibitors