Non-ischemic cardiomyopathy with focal segmental glomerulosclerosis

Parminder Kaur; Balraj Singh; Prem Patel; Rahul Vasudev; Upamanyu Rampal; Fayez Shamoon

doi:10.1080/20009666.2020.1742470

Non-ischemic cardiomyopathy with focal segmental glomerulosclerosis

J Community Hosp Intern Med Perspect. 2020 Mar 3;10(2):154-157. doi: 10.1080/20009666.2020.1742470.

Authors

Parminder Kaur¹, Balraj Singh¹, Prem Patel¹, Rahul Vasudev¹, Upamanyu Rampal¹, Fayez Shamoon¹

Affiliation

¹ Saint Joseph's University Medical Center, Paterson, NJ, 07013, USA.

Abstract

Focal segmental glomerulosclerosis (FSGS) is a common cause of nephrotic syndrome, accounting for 40% of nephrotic syndrome in adults. FSGS has diverse clinical and morphological features and underlying pathogenesis. We present a case of a 33-year-old male presenting with acute systolic heart failure complicated with left ventricular thrombus with embolism to coronary circulation and bilateral deep vein thrombosis. He was found to have nephrotic range proteinuria with kidney biopsy showing FSGS. Association of FSGS with cardiomyopathy has been reported in children. However, in adults, according to our best knowledge, there have not been any report of FSGS and non-ischemic cardiomyopathy or it is at least underreported.

Abbreviations: FSGS: Focal segmental glomerulosclerosis; ESRD: End-stage renal disease; NOS: Not otherwise specified; LV: Left ventricle.

Keywords: Focal segmental glomerulosclerosis; cardiomyopathy; left ventricle thrombus; nephrotic syndrome.

Publication types

Case Reports