Pigment-induced glaucoma secondary to bilateral diffuse uveal melanocytic proliferation

Eur J Ophthalmol. 2022 Jan;32(1):NP62-NP65. doi: 10.1177/1120672120953076. Epub 2020 Aug 25.

Abstract

We report the first case of pigment-induced glaucoma in a patient presenting with bilateral diffuse uveal melanocytic proliferation (BDUMP) syndrome. Despite treatment with plasma exchange, the patient developed progression of her lesions and bilateral glaucoma. Surgical treatment with Ahmed valve implant was performed to control her increased intra-ocular pressure. This case demonstrates that BDUMP can be a cause of a refractory pigment-induced glaucoma.

Keywords: Pigment; bilateral diffuse uveal melanocytic proliferation; paraneoplastic syndrome; pigmentary glaucoma.

MeSH terms

  • Cell Proliferation
  • Female
  • Glaucoma, Open-Angle* / etiology
  • Glaucoma, Open-Angle* / surgery
  • Humans
  • Melanocytes
  • Paraneoplastic Syndromes, Ocular*
  • Retinal Neoplasms*