Rapid Review of SARS-CoV-1 and SARS-CoV-2 Viability, Susceptibility to Treatment, and the Disinfection and Reuse of PPE, Particularly Filtering Facepiece Respirators

Int J Environ Res Public Health. 2020 Aug 22;17(17):6117. doi: 10.3390/ijerph17176117.

Abstract

In the COVID-19 pandemic caused by SARS-CoV-2, hospitals are often stretched beyond capacity. There are widespread reports of dwindling supplies of personal protective equipment (PPE), particularly N95-type filtering facepiece respirators (FFRs), which are paramount to protect frontline medical/nursing staff, and to minimize further spread of the virus. We carried out a rapid review to summarize the existing literature on the viability of SARS-CoV-2, the efficacy of key potential disinfection procedures against the virus (specifically ultraviolet light and heat), and the impact of these procedures on FFR performance, material integrity, and/or fit. In light of the recent discovery of SARS-CoV-2 and limited associated research, our review also focused on the closely related SARS-CoV-1. We propose a possible whole-of-PPE disinfection solution for potential reuse that could be rapidly instituted in many health care settings, without significant investments in equipment.

Keywords: COVID-19; N95; SARS-CoV-1; SARS-CoV-2; UVC; coronavirus; decontamination; disinfection; filtering facepiece respirators; heat; personal protective equipment; reuse; temperature; ultraviolet light; viability.

Publication types

  • Review

MeSH terms

  • Betacoronavirus / drug effects*
  • COVID-19
  • Coronavirus Infections
  • Disinfection*
  • Equipment Reuse*
  • Humans
  • Masks
  • Pandemics
  • Personal Protective Equipment*
  • Pneumonia, Viral
  • Respiratory Protective Devices
  • SARS-CoV-2
  • Severe Acute Respiratory Syndrome
  • Severe acute respiratory syndrome-related coronavirus / drug effects*