Elevated levels of calpain 14 in nasal tissue in chronic rhinosinusitis

Marina Boruk; Abdoulaye J Dabo; Sridesh Nath; Kanza Zahid; Magdalena Ploszaj; Derek Wu; Richard Rosenfeld; Robert F Foronjy; Patrick Geraghty

doi:10.1183/23120541.00137-2020

Elevated levels of calpain 14 in nasal tissue in chronic rhinosinusitis

ERJ Open Res. 2020 Aug 17;6(3):00137-2020. doi: 10.1183/23120541.00137-2020. eCollection 2020 Jul.

Authors

Marina Boruk¹, Abdoulaye J Dabo^{2

3}, Sridesh Nath², Kanza Zahid², Magdalena Ploszaj^{2

3}, Derek Wu¹, Richard Rosenfeld¹, Robert F Foronjy^{2

3}, Patrick Geraghty^{2

3}

Affiliations

¹ Dept of Otolaryngology, State University of New York Downstate Medical Center, Brooklyn, NY, USA.
² Dept of Medicine, State University of New York Downstate Medical Center, Brooklyn, NY, USA.
³ Dept of Cell Biology, State University of New York Downstate Medical Center, Brooklyn, NY, USA.

Abstract

Sinusitis is a common condition associated with inflammation in the sinuses and nasal mucosa. Calpain 14 is highly expressed in the nasal tissues of sinusitis subjects. Calpain 14 is associated with epithelial barrier disruption. https://bit.ly/3fyAwVO.