ALG8-RET: A novel RET rearrangement in a patient with malignant melanoma of the palatal mucosal

Oral Oncol. 2020 Dec:111:104973. doi: 10.1016/j.oraloncology.2020.104973. Epub 2020 Aug 19.

Authors

Dongliang Wei¹, Dongsheng Chen², Lijian Li², Jing Tian², Guoxin Ren³

Affiliations

¹ Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 210000, China.
² The State Key Laboratory of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Diagnostics Co., Ltd, Nanjing 210002, China.
³ Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 210000, China. Electronic address: guoxinjd@126.com.

PMID: 32826184
DOI: 10.1016/j.oraloncology.2020.104973

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Gene Fusion / genetics*
Glucosyltransferases / genetics*
Humans
Male
Melanoma / genetics*
Melanoma / therapy
Mouth Mucosa
Mutation
Palatal Neoplasms / genetics*
Palatal Neoplasms / therapy
Proto-Oncogene Proteins c-ret / antagonists & inhibitors
Proto-Oncogene Proteins c-ret / genetics*
Pyrazoles / therapeutic use
Pyridines / therapeutic use

Substances

Pyrazoles
Pyridines
selpercatinib
ALG8 protein, human
Glucosyltransferases
Proto-Oncogene Proteins c-ret
RET protein, human