This article addresses an output-feedback flocking control problem for a swarm of autonomous surface vehicles (ASVs) to follow a leading ASV guided via a parameterized path. The leading and following ASVs are subject to completely unknown model parameters, external disturbances, and unmeasured velocities. A data-driven adaptive anti-disturbance control method is proposed for establishing a flocking behavior without any prior knowledge of model parameters. Specifically, a data-driven adaptive extended state observer (ESO) is proposed such that unknown input gains, unmeasured velocities, and total disturbance are simultaneously estimated. For the leading ASV, an output-feedback path-following control law is developed to follow a predefined parameterized path. For following ASVs, an output-feedback flocking control law is developed based on an artificial potential function for collision avoidance and connectivity preservation, in addition to a distributed ESO for estimating the velocity of the leading ASV through a cooperative estimation network. The simulation results are discussed to substantiate the efficacy of the proposed path-guided output-feedback ASV flocking control based on data-driven adaptive ESOs without measured velocity information.