Clinical Features of Endogenous Endophthalmitis Secondary to Minimally Invasive Upper Urinary Tract Calculus Removal

Ocul Immunol Inflamm. 2022 Jan 2;30(1):104-110. doi: 10.1080/09273948.2020.1778732. Epub 2020 Aug 18.

Abstract

Purpose: To evaluate endogenous endophthalmitis clinical features following minimally invasive removal of upper urinary tract calculi.

Methods: Medical records of twelve patients (17 eyes) with endogenous endophthalmitis secondary to minimally invasive upper urinary tract calculus removal were retrospectively reviewed.

Results: Diabetes mellitus was found in 7 patients (58%). 10 patients (83%) suffered from fever. The stone extraction and ocular symptom onset interval ranged from 2 to 22 days. All eyes presented as vitritis and fluffy yellow-white retinal exudates. Hypopyon was only found in 3 eyes (18%). 5 patients (42%) were misdiagnosed as uveitis which led to mismanagement. Ocular fluids were culture positive for only C. albicans in 12 eyes (71%). 10 of 12 eyes (83%) with silicon oil tamponade obtained a final BCVA≥0.05.

Conclusions: C. albicans was the most common endogenous endophthalmitis pathogen after urinary calculus removal by minimally invasive surgery. Pars plana vitrectomy with silicon oil tamponade may be helpful to achieve a favorable visual outcome. Routine ophthalmologic evaluation by the uveitis or vitreoretinal specialist may be necessary within 2 weeks after the urological procedures.

Keywords: Urinary tract calculi; endophthalmitis; fungi; minimally invasive surgery; pars plana vitrectomy.

MeSH terms

  • Calculi* / surgery
  • Endophthalmitis* / diagnosis
  • Endophthalmitis* / etiology
  • Endophthalmitis* / surgery
  • Humans
  • Retrospective Studies
  • Treatment Outcome
  • Urinary Tract*
  • Visual Acuity
  • Vitrectomy / methods