Retinal Pigment Epithelial Detachment in Age-Related Macular Degeneration

Ophthalmol Ther. 2020 Dec;9(4):739-756. doi: 10.1007/s40123-020-00291-5. Epub 2020 Aug 18.

Abstract

Retinal pigment epithelial detachment is defined as a separation of the retinal pigment epithelium from the inner collagenous layer of Bruch's membrane. It is a common manifestation in both dry and wet types of age-related macular degeneration. This review aims to provide a comprehensive guide to the pathophysiology, clinical and imaging characteristics, natural course and treatment of the various types of pigment epithelial detachments in order to assist in diagnosis and management of this important feature of age-related macular degeneration.

Keywords: Age-related macular degeneration; Drusenoid; Fibrovascular; Haemorrhagic; Pigment epithelial detachment; Serous.

Publication types

  • Review