Widespread Metastatic Gastric Signet-Ring Cell Carcinoma Shown by 68Ga-FAPI PET/CT

Clin Nucl Med. 2021 Feb 1;46(2):e78-e79. doi: 10.1097/RLU.0000000000003245.

Abstract

The present study compared 68Ga-FAPI and 18F-FDG PET/CT in a patient with GSRCC (gastric signet-ring cell carcinoma). In this case, 68Ga-FAPI PET/CT shows much higher tumor-to-background contrast of primary tumor and reveals more metastatic lesions than 18F-FDG PET/CT. This case demonstrates that 68Ga-FAPI PET/CT outperforms 18F-FDG in identifying both primary and metastatic lesions in GSRCC.

MeSH terms

  • Carcinoma, Signet Ring Cell / diagnostic imaging*
  • Carcinoma, Signet Ring Cell / pathology*
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Positron Emission Tomography Computed Tomography*
  • Quinolines*
  • Stomach Neoplasms / diagnostic imaging*
  • Stomach Neoplasms / pathology*

Substances

  • 68Ga-FAPI
  • Quinolines