Glioneuronal Hamartomas in the Central Nervous System of Two Goats

T Wu; A Miller; M Jager; T Southard

doi:10.1016/j.jcpa.2020.06.003

Glioneuronal Hamartomas in the Central Nervous System of Two Goats

J Comp Pathol. 2020 Jul:178:10-15. doi: 10.1016/j.jcpa.2020.06.003. Epub 2020 Jul 22.

Authors

T Wu¹, A Miller¹, M Jager¹, T Southard²

Affiliations

¹ Section of Anatomic Pathology, Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA.
² Section of Anatomic Pathology, Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA. Electronic address: tls93@cornell.edu.

PMID: 32800102
DOI: 10.1016/j.jcpa.2020.06.003

Abstract

Two goats (6 months old and 5 years old) were evaluated for neurological signs including laboured breathing, stiffness and obtundation. Solitary masses were noted in the brainstem and spinal cord, respectively. Histopathology of both cases revealed the lesions were composed of a mixture of glial and neuronal cells, consistent with glioneuronal hamartomas. The cause of death was attributed to the mass in the 6-month-old, while the cause of death in the 5-year-old was attributed to listeriosis. Hamartomas of neural origin are rarely described in veterinary species, and this report represents the first report of glioneuronal hamartomas in goats.

Keywords: goat; hamartoma; neural.

Publication types

Case Reports

MeSH terms

Animals
Brain Neoplasms / diagnosis
Brain Neoplasms / pathology
Brain Neoplasms / veterinary*
Central Nervous System / pathology
Goat Diseases*
Goats
Hamartoma / diagnosis
Hamartoma / pathology
Hamartoma / veterinary*
Neuroglia / pathology
Neurons / pathology
Spinal Cord / pathology