Challenges of Treating a Patient With Advanced Prostate Cancer During the COVID-19 Pandemic

Oncology (Williston Park). 2020 Aug 12;34(8):317-319. doi: 10.46883/ONC.2020.3408.0317.

Abstract

A 78-year-old man had a medical history of hypertension, atrial fibrillation, chronic kidney disease, and metastatic castration-resistant prostate cancer (CRPC). He had progressed to first-line therapy for CRPC with abiraterone plus androgen-deprivation therapy (ADT) and as second-line therapy he was being treated with docetaxel, with biochemical progression in his last prostate specific antigen measurement. He was admitted to the hospital on April 2020, in the middle of the coronavirus disease 2019 (COVID-19) pandemic, because of painful bone lesions and deterioration of renal function.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Androgen Antagonists / therapeutic use
  • Androstenes / therapeutic use
  • Anticoagulants / therapeutic use*
  • Antineoplastic Agents / therapeutic use
  • Betacoronavirus
  • Bone Density Conservation Agents / therapeutic use
  • Bone Neoplasms / complications
  • Bone Neoplasms / drug therapy*
  • Bone Neoplasms / secondary
  • COVID-19
  • Cancer Pain / complications
  • Cancer Pain / therapy
  • Coronavirus Infections / complications
  • Coronavirus Infections / therapy*
  • Disease Progression
  • Docetaxel / therapeutic use
  • Drug Combinations
  • Eligibility Determination
  • Heparin, Low-Molecular-Weight / therapeutic use
  • Humans
  • Intensive Care Units / supply & distribution
  • Lopinavir / therapeutic use
  • Male
  • Oxygen Inhalation Therapy
  • Palliative Care*
  • Pandemics
  • Pneumonia, Viral / complications
  • Pneumonia, Viral / therapy*
  • Prostatic Neoplasms, Castration-Resistant / complications
  • Prostatic Neoplasms, Castration-Resistant / drug therapy*
  • Prostatic Neoplasms, Castration-Resistant / pathology
  • Renal Insufficiency
  • Respiratory Insufficiency / etiology
  • Respiratory Insufficiency / therapy*
  • Reverse Transcriptase Polymerase Chain Reaction
  • Ritonavir / therapeutic use
  • SARS-CoV-2
  • Severity of Illness Index
  • Zoledronic Acid / therapeutic use

Substances

  • Androgen Antagonists
  • Androstenes
  • Anticoagulants
  • Antineoplastic Agents
  • Bone Density Conservation Agents
  • Drug Combinations
  • Heparin, Low-Molecular-Weight
  • lopinavir-ritonavir drug combination
  • Docetaxel
  • Lopinavir
  • Zoledronic Acid
  • abiraterone
  • Ritonavir