Effects of the COVID-19 pandemic on myocardial perfusion imaging for ischemic heart disease

Eur J Nucl Med Mol Imaging. 2021 Feb;48(2):421-427. doi: 10.1007/s00259-020-04994-6. Epub 2020 Aug 11.

Abstract

Purpose: We assessed the effects of the COVID-19 pandemic on myocardial perfusion imaging (MPI) for ischemic heart disease during the lockdown imposed by the Italian Government.

Methods: We retrospectively reviewed the number and the findings of stress single-photon emission computed tomography (SPECT)-MPI performed between February and May 2020 during the COVID-19 pandemic at the University of Napoli Federico II. The number and the findings of stress SPECT-MPI studies acquired in the corresponding months of the years 2017, 2018, and 2019 were also evaluated for direct comparison.

Results: The number of stress SPECT-MPI studies performed during the COVID-19 pandemic (n = 123) was significantly lower (P < 0.0001) compared with the mean yearly number of procedures performed in the corresponding months of the years 2017, 2018, and 2019 (n = 413). Yet, the percentage of abnormal stress SPECT-MPI studies was similar (P = 0.65) during the pandemic (36%) compared with the mean percentage value of the corresponding period of the years 2017, 2018, and 2019 (34%).

Conclusion: The number of stress SPECT-MPI studies was significantly reduced during the COVID-19 pandemic compared with the corresponding months of the previous 3 years. The lack of difference in the prevalence of abnormal SPECT-MPI studies between the two study periods strongly suggests that many patients with potentially abnormal imaging test have been missed during the pandemic.

Keywords: COVID-19; Ischemic heart disease; SARS-CoV-2; SPECT-MPI; Southern Italy.

MeSH terms

  • Aged
  • COVID-19 / epidemiology*
  • Female
  • Humans
  • Italy
  • Male
  • Middle Aged
  • Myocardial Ischemia / diagnostic imaging*
  • Myocardial Perfusion Imaging / statistics & numerical data*
  • Quarantine / statistics & numerical data
  • Tomography, Emission-Computed, Single-Photon / statistics & numerical data*