Azole-resistant Candida albicans Spondylodiscitis After Bariatric Surgery: A Case Report

JBJS Case Connect. 2020 Jul-Sep;10(3):e19.00618. doi: 10.2106/JBJS.CC.19.00618.

Abstract

Case: We present a case of azole and partial caspofungin-resistant Candida albicans spondylodiscitis, after bariatric surgery with bowel perforation. Treatment included debridement and several months of anidulafungin, complemented with antibacterial therapy because of relapse for bacterial superinfection. After treatment, the infection did not recur clinically or radiologically during one and half years follow-up.

Conclusion: Although C. albicans spondylodiscitis is rare, fungi should be suspected as a causative agent. Adequate history, imaging and laboratory testing, and medical and surgical treatment should be performed to successfully eradicate the infection and resolve potential neurological deficits.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Infective Agents / therapeutic use
  • Bariatric Surgery / adverse effects*
  • Candida albicans / isolation & purification
  • Candida albicans / physiology*
  • Candidiasis / complications
  • Discitis / microbiology*
  • Drug Resistance, Multiple, Bacterial
  • Drug Resistance, Multiple, Fungal*
  • Female
  • Humans
  • Intestinal Perforation / complications
  • Jejunal Diseases / complications
  • Postoperative Complications / microbiology*
  • Shock, Septic / drug therapy
  • Shock, Septic / etiology
  • Spinal Fractures / microbiology
  • Spinal Fractures / surgery

Substances

  • Anti-Infective Agents