An Evidence-Based Care Protocol Improves Outcomes and Decreases Cost in Pediatric Appendicitis

J Surg Res. 2020 Dec:256:390-396. doi: 10.1016/j.jss.2020.05.067. Epub 2020 Aug 6.

Abstract

Background: Appendicitis is a common indication for urgent abdominal surgery in the pediatric population. The postoperative management varies significantly in time to discharge and cost of care. The objective of this study was to investigate whether implementation of an evidence-based protocol after an appendectomy would lead to decreased length of stay and cost of care.

Methods: In 2014 at the Children's Hospital of Pittsburgh, an initiative to develop an evidenced-based protocol to treat appendicitis was undertaken. A work group was formed of pediatric surgeons and other important personnel to determine best practices. Treatment pathways were created. Pathways differed with recommendation on postoperative antibiotic choice and duration, diet initiation, and discharge criteria. Data were prospectively gathered from all patients (ages 0-18 y) with acute appendicitis from January 2015 to December 2016. Primary outcomes were length of stay and cost of care. Secondary outcomes were surgical site infection, readmission rate, and duration of postoperative antibiotics.

Results: Among the 1289 patients, 481 patients were in the preprotocol cohort and 808 patients were in the postprotocol cohort. 27% of patients had an intraoperative diagnosis of complicated appendicitis. There was a significantly shorter length of stay in the postprotocol cohort (P < 0.001). Median costs for the whole cohort decreased 0.6% and 24.6% for patients with complicated appendicitis after protocol initiation (P < 0.01).

Conclusions: This study has demonstrated that introduction of an evidence-based clinical care protocol for pediatric patients with appendicitis leads to shorter hospital stay and decreased hospital costs.

Keywords: Appendicitis; Outcomes; Pediatrics; Protocols.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Appendectomy / adverse effects*
  • Appendicitis / economics
  • Appendicitis / surgery*
  • Child
  • Child, Preschool
  • Clinical Protocols / standards*
  • Evidence-Based Medicine / economics
  • Evidence-Based Medicine / organization & administration*
  • Evidence-Based Medicine / standards
  • Female
  • Health Plan Implementation / organization & administration
  • Hospital Costs / statistics & numerical data
  • Hospitals, Pediatric / economics
  • Hospitals, Pediatric / organization & administration
  • Hospitals, Pediatric / standards
  • Hospitals, Pediatric / statistics & numerical data
  • Humans
  • Infant
  • Infant, Newborn
  • Length of Stay / economics
  • Length of Stay / statistics & numerical data
  • Male
  • Patient Readmission / economics
  • Patient Readmission / statistics & numerical data
  • Postoperative Care / standards*
  • Practice Guidelines as Topic
  • Program Evaluation
  • Prospective Studies
  • Surgical Wound Infection / economics
  • Surgical Wound Infection / epidemiology*
  • Surgical Wound Infection / prevention & control
  • Treatment Outcome