Alcohol Pads and Nonsterile Gloves in Preparation of Aflibercept

Kathleen A Regan; Justin L Gottlieb; Michael M Altaweel; Mihai Mititelu; Barbara A Blodi; T Michael Nork; Kimberly E Stepien; Jonathan S Chang

doi:10.1016/j.oret.2020.04.006

Alcohol Pads and Nonsterile Gloves in Preparation of Aflibercept

Ophthalmol Retina. 2020 Aug;4(8):853-854. doi: 10.1016/j.oret.2020.04.006.

Authors

Kathleen A Regan¹, Justin L Gottlieb¹, Michael M Altaweel¹, Mihai Mititelu¹, Barbara A Blodi¹, T Michael Nork¹, Kimberly E Stepien¹, Jonathan S Chang²

Affiliations

¹ Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
² Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. Electronic address: Jschang4@wisc.edu.

Abstract

Use of nonsterile gloves and an alcohol pad does not significantly impact the contamination of the rubber septum of the aflibercept vial. Other contamination points might instead be explored for endophthalmitis risk.

MeSH terms

Angiogenesis Inhibitors / administration & dosage
Ethanol / pharmacology*
Gloves, Protective
Hand Disinfection / methods*
Humans
Intravitreal Injections / methods
Receptors, Vascular Endothelial Growth Factor / administration & dosage*
Recombinant Fusion Proteins / administration & dosage*

Substances

Angiogenesis Inhibitors
Recombinant Fusion Proteins
aflibercept
Ethanol
Receptors, Vascular Endothelial Growth Factor

Grants and funding

P30 EY016665/EY/NEI NIH HHS/United States