Quality of life and mental health are important outcomes of bariatric therapy. This review aimed to determine endoscopic bariatric procedures' impact on postprocedural quality of life and mental health. Four electronic databases were systematically searched. Studies with adults > 18 years who underwent an endoscopic bariatric procedure and reported pre- and postprocedural quality of life and/or mental health using a validated tool were included. Meta-analyses were conducted using RevMan and study quality was assessed. Twenty studies evaluating five different endoscopic procedures were included (N = 876 total sample size). Intragastric balloon placement was associated with a large improvement in postprocedural quality of life and mental health. Endoscopic bariatric therapies may improve short-term quality of life and mental health alongside weight loss and comorbidity improvement.
Keywords: Aspiration therapy; Duodenal bypass liner; Endoscopic bariatric therapy; Endoscopic sleeve gastroplasty; Intragastric balloon; Mental health; Obesity; Primary obesity surgery endoluminal; Quality of life; Transoral gastroplasty; Transpyloric shuttle.