Review: An insight into coronaviruses: Challenges, security and scope

Rev Med Virol. 2020 Nov;30(6):1-8. doi: 10.1002/rmv.2138. Epub 2020 Aug 4.

Abstract

SARS-CoV2 is a novel coronavirus; the seventh of its species to infect humans. The spread of this virus emerged in Wuhan, China in late December, 2019. Since then, this virus has spread to more than 200 countries and has caused a worldwide pandemic. Being a new species of coronaviruses, any cure or vaccines for this virus has not yet been obtained. A large amount of scientific studies and clinical trials are being carried out across the world to find a potential vaccine for this virus. Current work reports a review of potential drugs and vaccines that may be effective against this virus. Different scientific therapies that may potentially be effective against the SARS-CoV2 virus are also reviewed. The mechanisms of various drugs, their efficiency in various clinical trials and their side effects are also studied.

Keywords: FDA approved drug; affinity; coronavirus; infection; vaccines.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiviral Agents / pharmacology
  • Antiviral Agents / therapeutic use
  • COVID-19 / diagnosis
  • COVID-19 / prevention & control
  • COVID-19 / virology
  • COVID-19 Drug Treatment
  • Combined Modality Therapy
  • Coronavirus / drug effects
  • Coronavirus / physiology*
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / prevention & control
  • Coronavirus Infections / therapy*
  • Coronavirus Infections / virology*
  • Disease Susceptibility
  • Drug Development
  • Humans
  • Research
  • SARS-CoV-2 / drug effects
  • SARS-CoV-2 / physiology
  • Viral Vaccines / immunology

Substances

  • Antiviral Agents
  • Viral Vaccines