A Hypothesis for the Possible Role of Zinc in the Immunological Pathways Related to COVID-19 Infection

Front Immunol. 2020 Jul 10:11:1736. doi: 10.3389/fimmu.2020.01736. eCollection 2020.

Authors

Ander Mayor-Ibarguren¹, Carmen Busca-Arenzana², Ángel Robles-Marhuenda²

Affiliations

¹ Department of Dermatology, La Paz University Hospital, Madrid, Spain.
² Department of Internal Medicine, La Paz University Hospital, Madrid, Spain.

No abstract available

Keywords: COVID-19; IL-6; SARS-CoV-2; treatment; zinc.

MeSH terms

Adjuvants, Pharmaceutic
Antimalarials / therapeutic use
Betacoronavirus / enzymology
Betacoronavirus / immunology*
COVID-19
Coronavirus Infections / drug therapy
Coronavirus Infections / immunology*
Coronavirus Infections / mortality
Coronavirus Infections / virology
DNA-Directed RNA Polymerases / antagonists & inhibitors
Dietary Supplements
Drug Synergism
Homeostasis / immunology
Humans
Interferon Type I / immunology
Interleukin-6 / genetics
Interleukin-6 / immunology
Pandemics
Pneumonia, Viral / drug therapy
Pneumonia, Viral / immunology*
Pneumonia, Viral / mortality
Pneumonia, Viral / virology
Polymorphism, Genetic
SARS-CoV-2
Virus Replication / drug effects
Zinc / deficiency
Zinc / immunology*
Zinc / pharmacology
Zinc / therapeutic use

Substances

Adjuvants, Pharmaceutic
Antimalarials
IL6 protein, human
Interferon Type I
Interleukin-6
DNA-Directed RNA Polymerases
Zinc