Progress in Vaccination of Prophylactic Human Papillomavirus Vaccine

Front Immunol. 2020 Jul 10:11:1434. doi: 10.3389/fimmu.2020.01434. eCollection 2020.

Abstract

The human papillomavirus (HPV) vaccine plays an important role in preventing a series of diseases caused by HPV. Recent studies have shown that as a primary prevention measure, it can considerably prevent HPV infection and HPV-associated cervical cancer. However, studies on the safety, efficacy, and coverage of the HPV vaccine remain insufficient, especially in developing countries. Therefore, in this review, we outlined the recent studies of the HPV vaccine in terms of immunogenicity, safety, efficacy, latest vaccination concepts, and strategies. This review may provide a theoretical basis for use of the HPV vaccine.

Keywords: HPV; effectiveness; implementation; safety; vaccine.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alphapapillomavirus / physiology*
  • Female
  • Humans
  • Immunogenicity, Vaccine
  • Papillomavirus Infections / complications
  • Papillomavirus Infections / immunology*
  • Papillomavirus Vaccines / immunology*
  • Treatment Outcome
  • Uterine Cervical Neoplasms / etiology
  • Uterine Cervical Neoplasms / prevention & control*
  • Vaccination

Substances

  • Papillomavirus Vaccines