Association of GH, STAT5A, MYF5 gene polymorphisms with milk somatic cell count, EC and pH levels of Holstein dairy cattle

Anim Biotechnol. 2022 Jun;33(3):401-407. doi: 10.1080/10495398.2020.1800483. Epub 2020 Aug 4.

Abstract

This study was conducted to ivnestigate the associations of GH-AluI, STAT5A-AvaI and MYF5-TaqI gene polymorphisms with milk somatic cell count (SCC), electrical conductivity (EC) and pH levels in Holstein dairy cows. For this purpose, 167 blood and 1670 milk samples of 167 Holstein cows in their 2nd lactation were used. There were significant relationships between GH-AluI genotypes and milk EC (p < 0.001) and between STAT5A-AvaI genotypes and milk EC (p = 0.007), but there were not any significant relationships between MYF5 gene polymorphism and the investigated traits (p > 0.05). The greatest EC values were observed in GH-AluI-LV and STAT5A-AvaI-TT-genotyped individuals. Just because of association of EC with mastitis, it was concluded that present GH-AluI and STAT5A-AvaI polymorphisms could be used in further studies to be conducted to improve mastitis resistance and milk quality traits of Holstein dairy cows.

Keywords: PCR-RFLP; Growth related gene; bovine; milk quality traits.

MeSH terms

  • Animals
  • Cattle / genetics
  • Cattle Diseases*
  • Cell Count
  • Electric Conductivity
  • Female
  • Growth Hormone / genetics*
  • Hydrogen-Ion Concentration
  • Lactation / genetics
  • Mastitis, Bovine*
  • Milk
  • Myogenic Regulatory Factor 5 / genetics*
  • Polymorphism, Genetic / genetics
  • STAT5 Transcription Factor / genetics*

Substances

  • Myogenic Regulatory Factor 5
  • STAT5 Transcription Factor
  • Growth Hormone