Precision manipulation, or moving small objects held in the fingertips, is likely the most heavily utilized class of dexterous within-hand manipulation and adds greatly to the capabilities of the human hand. This article focuses on studying the effects of varying the number of digits used on the resulting manipulation abilities, in terms of translational workspaces and rotational ranges, by manipulating two circular objects, 50 mm and 80 mm in diameter. In general, as the number of digits in contact with the object increases, the results show a significant reduction in precision manipulation workspace range for four of the six translation and rotation directions and no significant change in the other two, suggesting that for these particular metrics, more fingers result in a reduction in performance. Furthermore, while two digits results in the largest workspaces for five of the six translation and rotation axes, the lack of ability to control rotation in the distal-proximal direction suggests that three digits may be more desirable for overall precision manipulation dexterity.