The relationship between circadian blood pressure variability and maternal/perinatal outcomes in women with preeclampsia with severe features

Hypertens Pregnancy. 2020 Nov;39(4):405-410. doi: 10.1080/10641955.2020.1797777. Epub 2020 Aug 3.

Abstract

Objective: To determine whether circadian blood pressure (BP) variation of women with preeclampsia (PE) with severe features was associated with adverse maternal/perinatal outcomes.

Methods: 173 women with PE with severe features were recruitedand categorized into three groups: dipper, non-dipper and reverse dipper type BP group.. Maternal and perinatal outcomes were compared among groups.

Results: There were significant differences in gestational ages, premature delivery, retinopathy, HELLP syndrome, mean birth weight, rate of low birth weight infants and fetal growth restriction.

Conclusion: Aberrant circadian pattern of BP in women with PE with severe features was associated with several adverse maternal/perinatal outcomes.

Keywords: Preeclampsia with severe features; blood pressure circadian; perinatal outcomes.

MeSH terms

  • Adolescent
  • Adult
  • Blood Pressure / physiology*
  • Blood Pressure Determination
  • Circadian Rhythm / physiology*
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Small for Gestational Age
  • Male
  • Middle Aged
  • Pre-Eclampsia / physiopathology*
  • Pregnancy
  • Pregnancy Outcome
  • Premature Birth / physiopathology*
  • Retrospective Studies
  • Young Adult