Diagnostic challenge of T-cell MALT lymphoma in oral cavity

Samuel Rocha França; Jefferson Douglas Lima Fernandes; Rodrigo Lemos Alves; Filipe Nobre Chaves; Denise Hélen Imaculada Pereira de Oliveira; Marcelo Bonifácio da Silva Sampieri

doi:10.1016/j.oraloncology.2020.104934

Diagnostic challenge of T-cell MALT lymphoma in oral cavity

Oral Oncol. 2020 Sep:108:104934. doi: 10.1016/j.oraloncology.2020.104934. Epub 2020 Jul 31.

Authors

Samuel Rocha França¹, Jefferson Douglas Lima Fernandes¹, Rodrigo Lemos Alves², Filipe Nobre Chaves¹, Denise Hélen Imaculada Pereira de Oliveira¹, Marcelo Bonifácio da Silva Sampieri¹

Affiliations

¹ Federal University of Ceará - Campus Sobral, Brazil.
² CTBMF Sector of Santa Casa de Misericórdia de Sobral, Brazil.

PMID: 32741729
DOI: 10.1016/j.oraloncology.2020.104934

Abstract

Mucosa-associated lymphoid tissue lymphoma (MALT) is a neoplasm of B cells from the extranodal marginal zone and a non-Hodgkin lymphoma subtype. We report a case of MALT lymphoma in the hard palate in a 74-year-old woman with the previous diagnosis of lymphoid hyperplasia. The intetion about this letter is to show the appropriate clinical conduct and the diagnostic challenge about this pathlogy in oral cavity, stressing the importance to incisional biopsy and immunohistochemical analysis to guide the right diagnostic of this rare lesion.

Keywords: B-Cell; Immunohistochemistry; Lymphoma; MALT lymphoma; Marginal zone; Non-Hodgkin lymphoma; Oral diagnosis.

Publication types

Letter

MeSH terms

Aged
Female
Humans
Immunohistochemistry / methods*
Lymphoma, B-Cell, Marginal Zone / diagnosis*
Mouth / pathology*