Pidotimod in allergic diseases

Minerva Pediatr. 2020 Oct;72(5):358-363. doi: 10.23736/S0026-4946.20.05967-8. Epub 2020 Jul 29.

Abstract

The rising incidence of allergic disease requires more specific, effective and safe therapeutic strategies. In this regard, several kinds of biologically active substances, commonly known as immunostimulants, have been introduced for the prevention and treatment of allergic diseases in pediatric population. Among the heterogeneous group of biologically active molecules to date available, pidotimod (Axil, Valeas S.p.A, Milan) is proved to be able to ameliorate both innate and adaptive immunity and enhances the immune system properties often impaired in patients with allergic disorders.

Publication types

  • Review

MeSH terms

  • Adaptive Immunity
  • Adjuvants, Immunologic / pharmacology
  • Adjuvants, Immunologic / therapeutic use*
  • Adolescent
  • Asthma / drug therapy
  • Asthma / immunology
  • Child
  • Child, Preschool
  • Chronic Urticaria / drug therapy
  • Dermatitis, Atopic / drug therapy
  • Dermatitis, Atopic / immunology
  • Desensitization, Immunologic
  • Food Hypersensitivity / drug therapy
  • Humans
  • Hypersensitivity / drug therapy*
  • Hypersensitivity / immunology
  • Immunity, Innate / drug effects
  • Immunologic Factors / pharmacology
  • Immunologic Factors / therapeutic use*
  • Pyrrolidonecarboxylic Acid / analogs & derivatives*
  • Pyrrolidonecarboxylic Acid / pharmacology
  • Pyrrolidonecarboxylic Acid / therapeutic use
  • Rhinitis, Allergic / drug therapy
  • Rhinitis, Allergic / immunology
  • Thiazolidines / pharmacology
  • Thiazolidines / therapeutic use*

Substances

  • Adjuvants, Immunologic
  • Immunologic Factors
  • Thiazolidines
  • pidotimod
  • Pyrrolidonecarboxylic Acid