Misdiagnosis of community-acquired pneumonia in patients admitted to respiratory wards, Penang General Hospital

Med J Malaysia. 2020 Jul;75(4):385-390.

Abstract

Introduction: Pneumonia continues to be as one of the top causes of hospitalisations and deaths in Malaysia despite the advancement in prevention and treatment of pneumonia. One of the possible explanations is the frequent misdiagnosis of pneumonia which had been reported elsewhere but such data is not available locally.

Objectives: This is an audit project aiming to evaluate the proportion of misdiagnosis among hospitalised communityacquired pneumonia (CAP) patients in the Respiratory wards of Penang General Hospital based on their initial presentation data, and their associated outcomes.

Methods: We reviewed the medical notes and initial chest radiographs of 188 CAP patients who were admitted to respiratory wards. Misdiagnosis was defined as cases which lack suggestive clinical features and/or chest radiograph changes. In-hospital mortality and length of stay (LOS) were the outcomes of interest.

Results: The study found that 38.8% (n=73) of the hospitalised CAP patients were misdiagnosed. The most common alternative diagnosis was upper respiratory tract infection (32.8%, n=24). There was no statistical difference between misdiagnosis and CAP patients in the demographic and clinical variables collected. In terms of outcomes, misdiagnosed patients were discharged earlier (mean LOS= 3.5±3.28 days vs. 7.7±15.29 days, p=0.03) but the in-hospital mortality difference was not statistically significant (p=0.07).

Conclusions: One third of our CAP admissions were misdiagnosed. Although initial misdiagnosis of CAP in our study did not show any increase in mortality or morbidity, a proper diagnosis of CAP will be helpful in preventing inappropriate prescription of antibiotics and unnecessary admission.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Community-Acquired Infections / diagnosis*
  • Diagnostic Errors* / statistics & numerical data
  • Female
  • Hospital Mortality
  • Hospitals, General
  • Humans
  • Length of Stay
  • Malaysia
  • Male
  • Medical Audit
  • Middle Aged
  • Pneumonia / diagnosis*
  • Prevalence