Recent Progress in Small-Molecule Fluorescent Probes for Detecting Mercury Ions

Crit Rev Anal Chem. 2022;52(2):250-274. doi: 10.1080/10408347.2020.1797466. Epub 2020 Jul 26.

Abstract

Mercury is a highly toxic and non-essential element that is found in every corner of the globe. The small amount of mercury produced by various pathways eventually enters freshwater and marine ecosystems, circulating through the food chain (especially fish) and causing various environmental problems in aspects including plants, animals, and human. There are several traditional quantitative methods developed for mercury ions (II) analysis in water samples. However, due to the complexity of the detection process, high cost and strong technical expertise, it is difficult to detect mercury ions in real-time. Therefore, in recent years, a large number of researchers have developed small-molecule fluorescent probes for Hg ions detection. Fluorimetry has the advantages of convenient detection, short response time, high sensitivity and good selectivity. This review summarized the small-molecule fluorescent probes for mercuric ion detection developed in recent years according to the chemical structural classification, compared their performances and elaborated the mechanism. We hope that the review will help the researches for the designs of metal ions fluorescent probes and their applications with certain reference value.

Keywords: Fluorescent probes; fluorophore; mercuric ion; sensitivity.

Publication types

  • Review

MeSH terms

  • Animals
  • Ecosystem
  • Fluorescent Dyes / chemistry
  • Humans
  • Ions / analysis
  • Mercury* / analysis
  • Mercury* / chemistry

Substances

  • Fluorescent Dyes
  • Ions
  • Mercury