A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection

Abdul Ahad Sohail; Bushra Ayub; Syed Akbar Abbas; Shafqat Ali Sheikh; Talha Ahmed Qureshi; Muhammad Usman; Asad Diwan

doi:10.1016/j.amsu.2020.07.023

A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection

Ann Med Surg (Lond). 2020 Jul 18:57:62-65. doi: 10.1016/j.amsu.2020.07.023. eCollection 2020 Sep.

Authors

Abdul Ahad Sohail¹, Bushra Ayub², Syed Akbar Abbas³, Shafqat Ali Sheikh², Talha Ahmed Qureshi², Muhammad Usman⁴, Asad Diwan⁴

Affiliations

¹ Department of Surgery, Aga Khan University Hospital, Pakistan.
² Patel Hospital, Pakistan.
³ Aga Khan University Hospital, Pakistan.
⁴ Department of Histopathology, Aga Khan University Hospital, Pakistan.

Abstract

Parathyroid carcinoma (PC) is one of the rarest malignancies making approximately 0.005% of all cancers. It may arise sporadically or less commonly, in conjunction with genetic endocrine syndromes. Due to the rarity of the disease, no general consensus or definitive guidelines exist for its pre-operative diagnosis, management, or follow up. Surgical tumor removal is the gold standard treatment to prevent its recurrence. Parathyroid carcinoma has a high recurrence rate ranging from 40 to 60% in recent literature. We report a case of a seventy-year-old elderly female with locally advanced parathyroid carcinoma successfully surgically excised completely with a 3 year disease free survival period without adjuvant chemotherapy or radiotherapy.

Keywords: Complete surgical resection; Parathyroid carcinomas; Primary hyperparathyroidism; Thyroid lobectomy.

Publication types

Case Reports