Background: A persistent craniopharyngeal canal (PCC) is a rare but treatable anatomical abnormality that causes recurrent meningitis and should be considered as a differential diagnosis.
Case report: We report a case of an 8-year-old boy who presented with recurrent meningitis associated to his PCC. Surgical repair was performed, and no further episodes occurred.
Keywords: Hypophyseal canal; Hypophyseal duct; Persistent craniopharyngeal canal; Recurrent bacterial meningitis; Skull base defects.