Invasive Fungal Infections at Presentation of Untreated Hematologic Malignancies: Rare and Elusive

Amy Spallone; Rachel S Hicklen; Dimitrios P Kontoyiannis

doi:10.1093/ofid/ofaa247

Invasive Fungal Infections at Presentation of Untreated Hematologic Malignancies: Rare and Elusive

Open Forum Infect Dis. 2020 Jul 18;7(7):ofaa247. doi: 10.1093/ofid/ofaa247. eCollection 2020 Jul.

Authors

Amy Spallone^{1

2}, Rachel S Hicklen³, Dimitrios P Kontoyiannis¹

Affiliations

¹ Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
² Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas, USA.
³ Research Medical Library, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Abstract

Invasive fungal infections (IFIs) are a feared complication of hematologic malignancy (HM) treatment. Infrequently, the diagnosis of a new IFI contemporaneously with a new untreated HM has been sporadically described in case reports. We performed a comprehensive search of published literature and reviewed cases describing this synchronous disease phenomenon.

Keywords: hematologic malignancy; invasive fungal infections; molds; yeasts.