Advances in Research on the Preparation and Biological Activity of Maslinic Acid

Abstract

Maslinic acid, a pentacyclic triterpene acid, is mainly isolated from olives. Maslinic acid and its derivatives exhibit a broad range of biological properties, such as anti-inflammatory, anticancer, anti-diabetic, antimicrobial, neuroprotective and hepatoprotective activities. In this minireview, the progress of research on maslinic acid with regard to its bioactivities, extraction, semisynthetic preparation and patents is reported. The relationships between the structure and the activity of maslinic acid and its derivatives are also discussed.

Keywords: Maslinic acid; biological activity; extraction; pentacyclic triterpene; semisynthetic; structure-activity relationships.