Kawasaki disease shock syndrome complicated with bilateral lung consolidation in a child: A case report

Medicine (Baltimore). 2020 Jul 17;99(29):e20998. doi: 10.1097/MD.0000000000020998.

Abstract

Introduction: Kawasaki disease (KD) is a systemic inflammatory disease. Standard imaging features of KD include interstitial and lobular inflammatory lesions in the lungs, while KD shock syndrome (KDSS), complicated with substantial consolidation and atelectasis in the lung, is rarely reported.

Patients concerns: Herein, we report a single case of a 5-year-old female patient who manifested KDSS on the seventh day of the course of KD. Chest enhanced computed tomography indicated large-area consolidation in the lower lobes of the bilateral lungs.

Diagnosis: The patient was diagnosed with KDSS complicated with non-infective lung consolidation.

Interventions: The patient received human intravenous immunoglobulin (2 g/kg) and aspirin (30-50 mg/kgd), methylprednisolone, a vasoactive agent, and albumin. Infective factors were excluded.

Outcomes: The consolidation in the lower lobe of the bilateral lungs was completely recovered after 3 days of treatment.

Conclusions: Children with KDSS may present with pulmonary lesions such as substantial consolidation and atelectasis; thus, infective factors should be excluded. If there is no etiological evidence, antibiotics should be used with caution.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Immunologic Factors / therapeutic use
  • Methylprednisolone / therapeutic use
  • Mucocutaneous Lymph Node Syndrome / complications*
  • Mucocutaneous Lymph Node Syndrome / diagnosis
  • Mucocutaneous Lymph Node Syndrome / therapy
  • Norepinephrine / therapeutic use
  • Pulmonary Atelectasis / diagnostic imaging
  • Pulmonary Atelectasis / etiology*
  • Pulmonary Atelectasis / therapy
  • Shock / etiology*
  • Shock / therapy
  • Tomography, X-Ray Computed
  • Vasoconstrictor Agents / therapeutic use

Substances

  • Glucocorticoids
  • Immunoglobulins, Intravenous
  • Immunologic Factors
  • Vasoconstrictor Agents
  • Norepinephrine
  • Methylprednisolone