Fluorescent angiography imaging of intravitreal active bleeding, due to deep venous thrombosis concomitant to Fournier gangrene

Eur J Ophthalmol. 2022 Jan;32(1):NP5-NP8. doi: 10.1177/1120672120945106. Epub 2020 Jul 22.

Abstract

Purpose: To report a breakthrough bleeding in the vitreous cavity due to deep venous thrombosis, in a case of a middle-aged male patient who suffered concomitantly from Fournier's gangrene. Fluorescent angiography imaging displayed the intravitreal hemorrhage as occurring.

Methods: We performed fundus fluorescein angiography and optical coherence tomography at baseline and follow-up examinations.

Results: During fluorescein angiography we identified, right eye fluorescent blockage corresponding to a pre-retinal, a subhyaloid, and an intraretinal hemorrhage in the posterior pole. Capillary non-perfusion, and capillary remodeling of the far temporal peripheral vasculature was detected as well, the left eye was unremarkable. A breakthrough bleeding in the vitreous cavity of the upper temporal vein branch was caught as it was happening. We did not observe leaking at the macula; our findings were confirmed with optical coherence tomography throughout the follow-up period.

Conclusion: Active retinal bleeding has been reported only twice in the past, in these cases, it was attributed to superficial venous vessel rupture due to vitreous traction or Valsalva-like retinopathy at the site of neovascularization. Active retinal vein bleeding during a fluorescein angiography, secondary to deep venous thrombosis due to Fournier gangrene, has not been previously reported.

Keywords: Fournier gangrene; intravitreal hemorrhage; retinal bleeding; venous thromboembolism.

Publication types

  • Case Reports

MeSH terms

  • Fluorescein Angiography
  • Fournier Gangrene*
  • Humans
  • Male
  • Middle Aged
  • Retinal Hemorrhage / diagnosis
  • Retinal Hemorrhage / etiology
  • Retinal Vein*
  • Tomography, Optical Coherence
  • Venous Thrombosis* / diagnosis
  • Venous Thrombosis* / diagnostic imaging