Targeting mitochondrial ion channels in Type 2 diabetes

Future Med Chem. 2020 Sep;12(17):1525-1527. doi: 10.4155/fmc-2020-0150. Epub 2020 Jul 23.

Authors

Andreas Wiederkehr¹, Jaime Santo-Domingo¹

Affiliation

¹ Department of Cell Biology, Nestlé Research, Lausanne, 1015, Switzerland.

PMID: 32698623
DOI: 10.4155/fmc-2020-0150

No abstract available

Keywords: MCU; VDAC; beta-cell; diabetes; ion channels; mitochondria.

Publication types

Editorial

MeSH terms

Animals
Diabetes Mellitus, Type 2 / drug therapy*
Diabetes Mellitus, Type 2 / metabolism
Diabetes Mellitus, Type 2 / pathology
Humans
Hypoglycemic Agents / chemistry
Hypoglycemic Agents / pharmacology*
Insulin-Secreting Cells / drug effects*
Insulin-Secreting Cells / metabolism
Mitochondria / drug effects*
Mitochondria / metabolism
Voltage-Dependent Anion Channels / antagonists & inhibitors*
Voltage-Dependent Anion Channels / metabolism

Substances

Hypoglycemic Agents
Voltage-Dependent Anion Channels