Left bundle branch pacing: A comprehensive review

J Cardiovasc Electrophysiol. 2020 Sep;31(9):2462-2473. doi: 10.1111/jce.14681. Epub 2020 Jul 30.

Abstract

Cardiac pacing is the only effective therapy for patients with symptomatic bradyarrhythmia. Traditional right ventricular apical pacing causes electrical and mechanical dyssynchrony resulting in left ventricular dysfunction, recurrent heart failure, and atrial arrhythmias. Physiological pacing activates the normal cardiac conduction, thereby providing synchronized contraction of ventricles. Though His bundle pacing (HBP) acts as an ideal physiological pacing modality, it is technically challenging and associated with troubleshooting issues during follow-up. Left bundle branch pacing (LBBP) has been suggested as an effective alternative to overcome the limitations of HBP as it provides low and stable pacing threshold, lead stability, and correction of distal conduction system disease. This paper will focus on the implantation technique, troubleshooting, clinical implications, and a review of published literature of LBBP.

Keywords: conduction system; dyssynchrony; heart failure; left bundle pacing; physiological pacing.

Publication types

  • Review

MeSH terms

  • Bundle of His*
  • Bundle-Branch Block* / diagnosis
  • Bundle-Branch Block* / therapy
  • Cardiac Pacing, Artificial
  • Electrocardiography
  • Heart Conduction System*
  • Humans