Non-Hodgkin's lymphoma: A review

Rohit Singh; Shabana Shaik; Bhupender Singh Negi; Jagadish Prasad Rajguru; Pankaj Bajirao Patil; Anuj Singh Parihar; Uma Sharma

doi:10.4103/jfmpc.jfmpc_1037_19

Non-Hodgkin's lymphoma: A review

J Family Med Prim Care. 2020 Apr 30;9(4):1834-1840. doi: 10.4103/jfmpc.jfmpc_1037_19. eCollection 2020 Apr.

Authors

Rohit Singh¹, Shabana Shaik², Bhupender Singh Negi³, Jagadish Prasad Rajguru⁴, Pankaj Bajirao Patil⁵, Anuj Singh Parihar⁶, Uma Sharma⁷

Affiliations

¹ Lecturer, Department of Prosthodontics, Crown Bridge and Implantology, Patna Dental College and Hospital, Patna, Bihar, India.
² Postgraduate Student, Department of Oral Medicine and Radiology, The Oxford Dental College, Bangalore, Karnataka, India.
³ Senior Resident, Department of Oral Medicine AND Radiology, Government Dental College Kottayam, Kerala, India.
⁴ Professor and HOD, Department of Oral and Maxillofacial Pathology, Hi-Tech Dental College and Hospital, Bhubaneswar, Odisha, India.
⁵ Assistant Professor, Department of Oral and Maxillofacial Surgery School of Dental Sciences, Krishna Institute of Medical Sciences, Deemed to be University, Karad, Maharashtra, India.
⁶ Reader, Department of Periodontology, People's Dental Academy, Bhopal, Madhya Pradesh, India.
⁷ Private Practitioner and Consultant Orthodontist, New Delhi, India.

Abstract

Lymphomas constitute the third most common neoplasm in head and neck region arising from the lymphoreticular system. Malignant lymphomas are divided into Hodgkin's disease and non-Hodgkin's lymphoma (NHL). NHL comprises approximately 5% of head and neck malignancies and displays a wide range of appearances comparable with Hodgkin's disease. Hodgkin's and non-Hodgkin's lymphomas are seen in the head and neck region, but extranodal disease, with or without lymph node involvement, is more common among NHL patients. Extranodal involvement includes the areas such as Waldeyer's ring (i.e., the tonsils, pharynx, and base of the tongue), salivary glands, orbit, paranasal sinuses, and thyroid glands. There are several classification systems for categorizing NHL out of which WHO classification for lymphoid neoplasms is mostly followed. This review describes the pathogenesis of NHL and explains some of the important NHL (Marginal zone B-cell Lymphoma, follicular lymphoma, mantle cell lymphoma).

Keywords: Cell; Non Hodgkin's lymphoma; lymphomas.

Publication types

Review