Evaluation of corneal structures in myopic eyes more than twenty-two years after photorefractive keratectomy

J Biophotonics. 2020 Oct;13(10):e202000138. doi: 10.1002/jbio.202000138. Epub 2020 Aug 7.

Abstract

The aim of this study is to evaluate corneal epithelial thickness (CET), corneal densitometry (CD) in 84 myopic eyes (57 patients) more than 22 years after photorefractive keratectomy, using anterior segment-optical coherence tomography (AS-OCT) and Scheimpflug imaging system. The CET was significantly higher in all operated eyes than in unoperated eyes in central sector. A statistically significant increase in CD in corneal anterior layer of central sector was shown in groups of operated eyes with greater ablation depth respect to unoperated eyes. While there was no significant difference in CD between the operated eyes groups with lower ablation depth and unoperated eyes. A significant trend toward higher values in anterior CD with deeper ablations in central sector was found. These noninvasive imaging techniques allow to better understand the corneal remodeling process after photoablation and to monitor the patients over time.

Keywords: anterior segment-optical coherence tomography; corneal densitometry; corneal epithelial thickness; photorefractive keratectomy; scheimpflug imaging system.

MeSH terms

  • Cornea* / diagnostic imaging
  • Cornea* / surgery
  • Humans
  • Myopia* / diagnostic imaging
  • Myopia* / surgery
  • Photorefractive Keratectomy*
  • Tomography, Optical Coherence