Bioactive Polysaccharides from Seaweeds

Molecules. 2020 Jul 9;25(14):3152. doi: 10.3390/molecules25143152.

Abstract

Bioactive compounds with diverse chemical structures play a significant role in disease prevention and maintenance of physiological functions. Due to the increase in industrial demand for new biosourced molecules, several types of biomasses are being exploited for the identification of bioactive metabolites and techno-functional biomolecules that are suitable for the subsequent uses in cosmetic, food and pharmaceutical fields. Among the various biomasses available, macroalgae are gaining popularity because of their potential nutraceutical and health benefits. Such health effects are delivered by specific diterpenes, pigments (fucoxanthin, phycocyanin, and carotenoids), bioactive peptides and polysaccharides. Abundant and recent studies have identified valuable biological activities of native algae polysaccharides, but also of their derivatives, including oligosaccharides and (bio)chemically modified polysaccharides. However, only a few of them can be industrially developed and open up new markets of active molecules, extracts or ingredients. In this respect, the health and nutraceutical claims associated with marine algal bioactive polysaccharides are summarized and comprehensively discussed in this review.

Keywords: Macroalgae; bioactive agents; biomolecules; polysaccharides; seaweeds.

Publication types

  • Review

MeSH terms

  • Carotenoids / chemistry
  • Carotenoids / therapeutic use
  • Dietary Supplements*
  • Humans
  • Peptides / chemistry
  • Peptides / therapeutic use
  • Polysaccharides* / chemistry
  • Polysaccharides* / therapeutic use
  • Seaweed / chemistry*
  • Xanthophylls / chemistry
  • Xanthophylls / therapeutic use

Substances

  • Peptides
  • Polysaccharides
  • Xanthophylls
  • fucoxanthin
  • Carotenoids