Intrauterine Transmission of SARS-COV-2 Infection in a Preterm Infant

Pediatr Infect Dis J. 2020 Sep;39(9):e265-e267. doi: 10.1097/INF.0000000000002815.

Abstract

We present a preterm infant who developed a fever and mild respiratory disease on the second day of life. Infant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nasopharyngeal testing was positive at 24 and 48 hours of life. Placenta histopathology revealed SARS-CoV-2 infection by electron microscopy and immunohistochemistry. Further understanding of the risk factors that lead to in utero transmission of SARS-CoV-2 infection is needed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Betacoronavirus / isolation & purification
  • COVID-19
  • Coronavirus Infections / transmission*
  • Coronavirus Infections / virology
  • Female
  • Fever / virology
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Infectious Disease Transmission, Vertical*
  • Pandemics
  • Placenta / pathology
  • Pneumonia, Viral / transmission*
  • Pneumonia, Viral / virology
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / virology*
  • Risk Factors
  • SARS-CoV-2