Typical Acute Traumatic Fracture Healing in an 83-Year-Old Man Undergoing 223Ra Treatment for Prostatic Cancer Bone Metastases

Clin Nucl Med. 2020 Sep;45(9):683-686. doi: 10.1097/RLU.0000000000003173.

Abstract

We report the case of a fracture healing after Ra in an 83-year-old wheelchair-bound man with prostate castration-resistant adenocarcinoma treated due to uncontrollable pain from widespread bone metastases. The patient fractured both right tibia and fibula 15 days prior to the first Ra cycle. After the first cycle, there was complete remission of his metastatic bone pain; after the second cycle, he began walking with support, which helped improve fracture healing; and after the third cycle, he presented complete mobility. Posttreatment images showed consolidated fractures. By improving metastatic bone pain with Ra, consolidation of the insufficiency fracture was possible.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Bone Neoplasms / physiopathology
  • Bone Neoplasms / radiotherapy*
  • Bone Neoplasms / secondary*
  • Fracture Healing*
  • Humans
  • Male
  • Prostatic Neoplasms / pathology*
  • Radium / therapeutic use*
  • Tibial Fractures / physiopathology*

Substances

  • Radium-223
  • Radium