Resistance Exercise in a Hot Environment Alters Serum Markers in Untrained Males

Arezoo Eskandari; Mohamad Fashi; Ayoub Saeidi; Daniel Boullosa; Ismail Laher; Abderraouf Ben Abderrahman; Gerorges Jabbour; Hassane Zouhal

doi:10.3389/fphys.2020.00597

Resistance Exercise in a Hot Environment Alters Serum Markers in Untrained Males

Front Physiol. 2020 Jun 23:11:597. doi: 10.3389/fphys.2020.00597. eCollection 2020.

Authors

Arezoo Eskandari¹, Mohamad Fashi², Ayoub Saeidi³, Daniel Boullosa^{4

5}, Ismail Laher⁶, Abderraouf Ben Abderrahman⁷, Gerorges Jabbour⁸, Hassane Zouhal⁹

Affiliations

¹ Department of Exercise Physiology, Faculty of Physical Education and Sports Science, Tehran University, Tehran, Iran.
² Department of Exercise Physiology, Faculty of Physical Education and Health Sciences, Shahid Beheshti University, Tehran, Iran.
³ Department of Physical Education, Damghan Branch, Islamic Azad University, Damghan, Iran.
⁴ INISA, Federal University of Mato Grosso do Sul, Campo Grande, Brazil.
⁵ Sport and Exercise Science, James Cook University, Townsville, Australia.
⁶ Department of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
⁷ ISSEP Ksar Said, University of Manouba, Tunis, Tunisia.
⁸ University of Qatar, Doha, Qatar.
⁹ Université de Rennes, M2S (Laboratoire Mouvement, Sport, Santé) - EA 1274, Rennes, France.

Abstract

Purpose: We examined the effects of moderate resistance exercise (RE) on serum cortisol, testosterone, extracellular heat shock protein (HSP70), and interleukin (IL)-6 and IL-15 concentrations in untrained males in a hot environment. Methods: Ten untrained young males (26 ± 3 years; 75.8 ± 6 kg; 177.4 ± 5.3 cm) performed two series of full body RE [3 sets of 8 to 10 repetitions, 30-60 s recovery between series with 70% of one maximal repetition (1-RM), with a rest period of 1 to 3 min between exercises] carried out in a random order in both heated (∼35°C) and thermoneutral (22°C) conditions. Serum concentrations of testosterone, cortisol, HSP70, and IL-6 and IL-15 were measured before, at the end, and 1 h after RE sessions. Participants in both groups consumed 4 ml of water/kg body mass every 15 min. Results: There were time-related changes in testosterone, HSP70, and IL-6 (P < 0.001), and cortisol and IL-15 (P < 0.05). Levels of cortisol, HSP70, and IL-6 increased immediately for RE at 35°C, and testosterone and IL-15 levels were decreased. Changes in serum testosterone, HSP70, cortisol, and IL-15 and IL-6 levels were reversed after 1 h. A significant time × condition interaction was observed for IL-15 and HSP70 (P < 0.001), cortisol and IL-6 (P < 0.05), but not for testosterone (P > 0.05). Conclusion: RE in a heated environment may not be appropriate for achieving muscle adaptations due to acute changes of hormonal and inflammatory markers.

Keywords: Interleukin 15; cytokines; heat; hypertrophy; nterleukin 6; resistance exercise; untrained young.