Muscle-Cell-Based "Living Diodes"

Uryan Isik Can; Neerajha Nagarajan; Dervis Can Vural; Pinar Zorlutuna

doi:10.1002/adbi.201600035

Muscle-Cell-Based "Living Diodes"

Adv Biosyst. 2017 Feb;1(1-2):e1600035. doi: 10.1002/adbi.201600035. Epub 2017 Jan 11.

Authors

Uryan Isik Can¹, Neerajha Nagarajan², Dervis Can Vural³, Pinar Zorlutuna^{1

2}

Affiliations

¹ Aerospace and Mechanical Engineering Department, University of Notre Dame, Notre Dame, IN, 46556, USA.
² Aerospace and Mechanical Engineering Department, Bioengineering Graduate Program, University of Notre Dame, Notre Dame, IN, 46556, USA.
³ Department of Physics, University of Notre Dame, Notre Dame, IN, 46556, USA.

PMID: 32646185
DOI: 10.1002/adbi.201600035

Abstract

A new type of diode that is made entirely of electrically excitable muscle cells and nonexcitable fibroblast cells is designed, fabricated, and characterized. These two cell types in a rectangular pattern allow the signal initiated on the excitable side to pass to the nonexcitable side, and not in the opposite direction.

Keywords: biocomputing; cell patterning; diodes; iontronics; muscle cells.

Grants and funding

1530884/NSF