COVID-19 scenario modelling for the mitigation of capacity-dependent deaths in intensive care

Health Care Manag Sci. 2020 Sep;23(3):315-324. doi: 10.1007/s10729-020-09511-7. Epub 2020 Jul 8.

Abstract

Managing healthcare demand and capacity is especially difficult in the context of the COVID-19 pandemic, where limited intensive care resources can be overwhelmed by a large number of cases requiring admission in a short space of time. If patients are unable to access this specialist resource, then death is a likely outcome. In appreciating these 'capacity-dependent' deaths, this paper reports on the clinically-led development of a stochastic discrete event simulation model designed to capture the key dynamics of the intensive care admissions process for COVID-19 patients. With application to a large public hospital in England during an early stage of the pandemic, the purpose of this study was to estimate the extent to which such capacity-dependent deaths can be mitigated through demand-side initiatives involving non-pharmaceutical interventions and supply-side measures to increase surge capacity. Based on information available at the time, results suggest that total capacity-dependent deaths can be reduced by 75% through a combination of increasing capacity from 45 to 100 beds, reducing length of stay by 25%, and flattening the peak demand to 26 admissions per day. Accounting for the additional 'capacity-independent' deaths, which occur even when appropriate care is available within the intensive care setting, yields an aggregate reduction in total deaths of 30%. The modelling tool, which is freely available and open source, has since been used to support COVID-19 response planning at a number of healthcare systems within the UK National Health Service.

Keywords: COVID-19; Capacity management; Coronavirus; Intensive care; Operations research; Simulation.

MeSH terms

  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections / epidemiology*
  • Critical Care / organization & administration
  • England / epidemiology
  • Health Services Needs and Demand / organization & administration*
  • Hospitals, Public / organization & administration
  • Humans
  • Intensive Care Units / organization & administration*
  • Models, Theoretical*
  • Pandemics
  • Pneumonia, Viral / epidemiology*
  • SARS-CoV-2
  • State Medicine / organization & administration*