Pathology and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Henok Kessete Afewerky

doi:10.1177/1535370220942126

Pathology and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Exp Biol Med (Maywood). 2020 Sep;245(15):1299-1307. doi: 10.1177/1535370220942126. Epub 2020 Jul 7.

Author

Henok Kessete Afewerky^{1

2

3}

Affiliations

¹ Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
² Department of Pathology and Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
³ School of Allied Health Professions, Asmara College of Health Sciences, Asmara 00291, Eritrea.

Abstract

The current survey of studies outlines the direct and indirect effects of SARS-CoV-2 on the specific body systems and summarizes the SARS-CoV-2 main pathogenicity mechanisms that require attention during patient hospitalization and for further research.

Keywords: COVID-19; Coronavirus; SARS-CoV-2; pathogenicity; pathology.

Publication types

Review

MeSH terms

Betacoronavirus / pathogenicity*
Betacoronavirus / physiology
COVID-19
Cardiovascular Diseases / etiology*
Coronavirus Infections / complications
Coronavirus Infections / pathology*
Coronavirus Infections / virology
Gastrointestinal Diseases / etiology*
Humans
Nervous System Diseases / etiology*
Pandemics
Pneumonia, Viral / complications
Pneumonia, Viral / pathology*
Pneumonia, Viral / virology
SARS-CoV-2
Virus Internalization
Virus Replication