Association between mutated Mas-related G protein-coupled receptor-X2 and rocuronium-induced intraoperative anaphylaxis

Br J Anaesth. 2020 Dec;125(6):e446-e448. doi: 10.1016/j.bja.2020.05.046. Epub 2020 Jul 2.

Authors

Yasuyuki Suzuki¹, Shuang Liu², Fumito Kadoya³, Yasushi Takasaki², Toshihiro Yorozuya², Masaki Mogi²

Affiliations

¹ Matsuyama City, Ehime, Japan. Electronic address: ysuzuki1978@gmail.com.
² Toon City, Ehime, Japan.
³ Matsuyama City, Ehime, Japan.

PMID: 32622467
DOI: 10.1016/j.bja.2020.05.046

No abstract available

Keywords: MRGPRX2; allergy testing; anaphylaxis; neuromuscular blocking agent; non-IgE-mediated allergic reaction; rocuronium.

Publication types

Case Reports
Letter

MeSH terms

Adrenergic alpha-Agonists / therapeutic use
Adult
Anaphylaxis / chemically induced*
Anaphylaxis / drug therapy
Anaphylaxis / genetics
Glucocorticoids / therapeutic use
Humans
Intraoperative Complications / chemically induced*
Intraoperative Complications / drug therapy
Male
Methylprednisolone / therapeutic use
Mutation / genetics*
Nerve Tissue Proteins / genetics*
Neuromuscular Nondepolarizing Agents / adverse effects
Norepinephrine / therapeutic use
Receptors, G-Protein-Coupled / genetics*
Receptors, Neuropeptide / genetics*
Rocuronium / adverse effects*

Substances

Adrenergic alpha-Agonists
Glucocorticoids
MRGPRX2 protein, human
Nerve Tissue Proteins
Neuromuscular Nondepolarizing Agents
Receptors, G-Protein-Coupled
Receptors, Neuropeptide
Rocuronium
Norepinephrine
Methylprednisolone