Lactose Intolerance: A Concise Review to Skim the Surface

Claire L Jansson-Knodell; Edward J Krajicek; Dennis A Savaiano; Andrea S Shin

doi:10.1016/j.mayocp.2020.04.036

Lactose Intolerance: A Concise Review to Skim the Surface

Mayo Clin Proc. 2020 Jul;95(7):1499-1505. doi: 10.1016/j.mayocp.2020.04.036.

Authors

Claire L Jansson-Knodell¹, Edward J Krajicek¹, Dennis A Savaiano², Andrea S Shin³

Affiliations

¹ Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, IN.
² Department of Nutrition Science, Purdue University, West Lafayette, IN.
³ Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, IN. Electronic address: ashin@iu.edu.

PMID: 32622451
DOI: 10.1016/j.mayocp.2020.04.036

Abstract

Lactose intolerance is a common but poorly understood cause of gastrointestinal symptoms. Contrary to popular belief, there is much more to its diagnosis beyond symptoms with exposure and management beyond milk- and dairy-product avoidance. In this article, we review definitions, genetic basis, pathogenesis, clinical signs, as well as diagnostic and management strategies.

Publication types

Review

MeSH terms

Dairy Products / adverse effects
Dairy Products / analysis
Humans
Lactose Intolerance* / diagnosis
Lactose Intolerance* / genetics
Lactose Intolerance* / physiopathology
Lactose Intolerance* / therapy