Treatment concerns for bullous pemphigoid in the COVID-19 pandemic era

Dermatol Ther. 2020 Nov;33(6):e13956. doi: 10.1111/dth.13956. Epub 2020 Jul 25.

Abstract

Bullous pemphigoid (BP) is the most common autoimmune blistering disease with subepidermal involvement, typically affecting the elderly. It has spontaneous remissions and exacerbations with significant morbidity. A novel coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the new universal coronavirus disease 2019 (COVID-19) pandemic. The pandemic made concerns, especially about immunosuppressive therapy. In this article, we reviewed the management of BP in the COVID-19 pandemic era. The data about the best management of autoimmune bullous diseases like BP, during the outbreak of COVID-19, are evolving and updated every day.

Keywords: COVID-19; Dermatologic Therapy; autoimmune bullous disease.

Publication types

  • Review

MeSH terms

  • Autoimmunity / drug effects*
  • COVID-19 / epidemiology
  • COVID-19 / immunology
  • COVID-19 / virology*
  • Host-Pathogen Interactions
  • Humans
  • Immunocompromised Host
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use*
  • Pemphigoid, Bullous / drug therapy*
  • Pemphigoid, Bullous / epidemiology
  • Pemphigoid, Bullous / immunology
  • Risk Assessment
  • Risk Factors
  • SARS-CoV-2 / drug effects
  • SARS-CoV-2 / immunology
  • SARS-CoV-2 / pathogenicity*
  • Treatment Outcome

Substances

  • Immunosuppressive Agents