A brief review of liver injury in patients with Corona Virus Disease-19 during the pandemic

Indian J Gastroenterol. 2020 Jun;39(3):232-235. doi: 10.1007/s12664-020-01068-1. Epub 2020 Jul 3.

Abstract

The novel coronavirus Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) infection has been mostly leading to respiratory distress syndrome, but liver injury has also been documented. The mechanism of liver injury is limited and poorly understood. However, the hepatic injury could be due to a consequence of systemic inflammatory response, viral infection of hepatocytes, or as a result of intensive care treatment or drug toxicity. Based on the current studies, this review article emphasizes on the demographic and potential mechanisms of Corona Virus Disease (COVID)-19-related liver dysfunction.

Keywords: COVID-19; Liver injury; Liver transplant.

Publication types

  • Review

MeSH terms

  • Betacoronavirus / physiology*
  • COVID-19
  • Coronavirus Infections* / epidemiology
  • Coronavirus Infections* / therapy
  • Coronavirus Infections* / virology
  • Host Microbial Interactions / physiology
  • Humans
  • Liver Diseases* / diagnosis
  • Liver Diseases* / epidemiology
  • Liver Diseases* / etiology
  • Liver Diseases* / metabolism
  • Liver Function Tests / methods
  • Pandemics*
  • Pneumonia, Viral* / epidemiology
  • Pneumonia, Viral* / therapy
  • Pneumonia, Viral* / virology
  • SARS-CoV-2