Dopamine and serotonin mediate the impact of stress on cleaner fish cooperative behavior

Murilo S de Abreu; Caio Maximino; Sónia C Cardoso; Cristiana I Marques; Ana F N Pimentel; Elona Mece; Svante Winberg; Leonardo J G Barcellos; Marta C Soares

doi:10.1016/j.yhbeh.2020.104813

Dopamine and serotonin mediate the impact of stress on cleaner fish cooperative behavior

Horm Behav. 2020 Sep:125:104813. doi: 10.1016/j.yhbeh.2020.104813. Epub 2020 Jul 17.

Authors

Murilo S de Abreu¹, Caio Maximino², Sónia C Cardoso³, Cristiana I Marques³, Ana F N Pimentel², Elona Mece⁴, Svante Winberg⁴, Leonardo J G Barcellos⁵, Marta C Soares⁶

Affiliations

¹ Bioscience Institute, University of Passo Fundo (UPF), Passo Fundo, RS, Brazil. Electronic address: abreu_murilo@hotmail.com.
² Laboratory of Neuroscience and Behavior "Frederico Guilherme Graeff", Federal University of Southern and Southeastern Pará, Marabá, PA, Brazil; Faculty of Psychology, Federal University of Southern and Southeastern Pará, Marabá, PA, Brazil.
³ CIBIO/InBIO, Research Centre in Biodiversity and Genetic Resources, University of Porto, 4485-661 Vairão, Portugal.
⁴ Department of Neuroscience, Uppsala University, Box 593, Husargatan 3, 75124 Uppsala, Sweden.
⁵ Graduate Programs in Bio-Experimentation and Environmental Sciences, University of Passo Fundo (UPF), Passo Fundo, Brazil; Graduate Program in Pharmacology, Federal University of Santa Maria (UFSM), Santa Maria, Brazil.
⁶ CIBIO/InBIO, Research Centre in Biodiversity and Genetic Resources, University of Porto, 4485-661 Vairão, Portugal. Electronic address: marta.soares@cibio.up.pt.

PMID: 32619442
DOI: 10.1016/j.yhbeh.2020.104813

Abstract

Stress is known to modulate behavioral responses and rapid decision-making processes, especially under challenging contexts which often occur in social and cooperative interactions. Here, we evaluated the effects of acute stress on cooperative behavior of the Indo-Pacific cleaner wrasse (Labroides dimidiatus) and the implications of pre-treatment with monoaminergic compounds: the selective serotonin reuptake inhibitor - fluoxetine, the 5-HT_1A receptor antagonist - WAY-100,635, the D₁ receptor agonist - SKF-38393, and the D₁ receptor antagonist - SCH-23390. We demonstrated that stress decreased the predisposal to interact and increased cortisol levels in cleaners, which are alleviated by fluoxetine and the dopaminergic D₁ antagonist. Overall, our findings highlight the crucial influence of stress on cooperative behavior.

Keywords: Cleaner wrasse; Cortisol; Dopamine; Serotonin; Social interaction; Tactile stimulation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine / pharmacology
Animals
Behavior, Animal / drug effects
Behavior, Animal / physiology
Benzazepines / pharmacology
Cooperative Behavior*
Dopamine / metabolism
Dopamine / physiology*
Dopamine Antagonists / pharmacology
Fishes / physiology
Fluoxetine / pharmacology
Perciformes / metabolism
Perciformes / physiology*
Piperazines / pharmacology
Pyridines / pharmacology
Receptors, Dopamine D1 / agonists
Receptors, Dopamine D1 / antagonists & inhibitors
Receptors, Dopamine D1 / drug effects
Serotonin / metabolism
Serotonin / physiology*
Stress, Physiological / drug effects
Stress, Physiological / physiology*

Substances

Benzazepines
Dopamine Antagonists
Piperazines
Pyridines
Receptors, Dopamine D1
SCH 23390
Fluoxetine
Serotonin
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide
Dopamine