Parecoxib for opioid-induced hyperalgesia

BMJ Support Palliat Care. 2021 Jun;11(2):126-127. doi: 10.1136/bmjspcare-2020-002290. Epub 2020 Jun 29.

Abstract

This paper describes the case report of a patient admitted to hospital with severe and complex pain and subacute bowel obstruction, who failed to respond to multiple analgesic regimens including ketamine burst and opioid rotation, and was subsequently successfully managed with a parecoxib infusion.

Keywords: cancer; drug administration; pain; supportive care.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Analgesics, Opioid / adverse effects*
  • Cancer Pain / drug therapy*
  • Humans
  • Hyperalgesia / chemically induced*
  • Hyperalgesia / drug therapy*
  • Isoxazoles / therapeutic use*
  • Male
  • Treatment Outcome

Substances

  • Analgesics, Opioid
  • Isoxazoles
  • parecoxib